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biG 412 - Mab to human LBP, IgG2a, (inhibit LPS binding to CD14)

Size

Order number: 023-3c.2

 

Delivery time on request

€180.00 *
 
 
 
 
 

Product information "biG 412 - Mab to human LBP, IgG2a, (inhibit LPS binding to CD14)"

Category

Mouse monoclonal antibody - Protein G purified - lyophilized

Reconstitution

For reconstitution add 50 µl distilled water.

Isotype

IgG1

Antigen

LBP knock out mouse immunized with immunoaffinity purified recombinant human LBP,a 58KD glycoprotein.

Special note

It is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (LPS) to elicit immune responses by presenting the LPS to CD14 and TLR4.

Characteristic

Inhibition of LPS binding to membrane bound CD14, inhibition titre 1:1000
Binding titre at human LBP- ELISA: 1:50.000 Antibody directly influenced interaction of CD14-LPS-LBP, binding site is at C-terminal site of LBP.

Application

ELISA, LBP inhibition studies

Storage

Long time storage at –20°C or –80°C

Quantity

100 µg in PBS without NaN3 or other stabilisation before lyophilisation

IgG-content 2 mg/ml (determined by mouse IgG-ELISA)

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Material Safety Data Sheet - Proteins and Antibodies